Lipides, Nutrition, Cancer
Selenocysteine: a 21st amino acid in the 21st Century
Background: Life scientists are often taught that proteins are comprised of a basic set of twenty amino acids. However, during the 1970's, it was discovered that a small subset of proteins contain selenocysteine, a 21st amino acid. Selenocysteine is structurally similar to cysteine, apart from it contains a selenium rather than a sulphur atom: this gives selenoproteins unique biochemical properties, particularly in terms of redox reactions. In this lecture, John Mackrill will review selenoprotein biology, particularly in terms of how selenium-containing proteins interact with lipids and calcium signalling mechanisms. He will also summarise some of the selenoprotein research that has been carried out in his laboratory.
Invitation: Gérard Lizard Equipe d'Accueil Bio-PeroxIL (EA7270
Le séminaire aura lieu à la Faculté de Médecine Dijon, Amphi Courtois à 11h00
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